Complete List of all Monographs and Supplements published to date
In the first 88 volumes of Monographs series, some 900 agents (chemicals, groups of chemicals, complex mixtures, occupational exposures, cultural habits, biological or physical agents) have been evaluated.
Each monograph consists of a brief description, where appropriate,of the potential exposure to the agent or mixture, by providing data on chemical and physical properties, methods of analysis, methods and volumes of production, use and occurrence. For exposure circumstances, a history and description of the exposure are given. Then, the relevant epidemiological studies are summarized. Subsequent sections cover evidence for carcinogenicity obtained in experimental animals, and a brief description of other relevant data, such as toxicity and genetic effects. The Agency makes every effort to ensure that the factual material presented is reported without bias, and it is meticulously checked for accuracy.
The Monographs are used widely by research scientists, public health authorities and national and international regulatory authorities. These users apply the information contained in the monographs in different ways, but it is hoped that none use the overall evaluations of carcinogenicity in isolation from the body of scientific evidence on which they are based.
Group 1: The agent (mixture) is carcinogenic to humans. The exposure circumstance entails exposures that are carcinogenic to humans.
Group 2 (two classifications):
Group 2A: The agent (mixture) is
probably carcinogenic to humans. The exposure circumstance entails
exposures that are probably carcinogenic to humans.
Group 2B: The agent (mixture) is possibly carcinogenic to humans. The exposure circumstance entails exposures that are possibly carcinogenic to humans.
Group 3: The agent (mixture, or exposure circumstance) is not classifiable as to carcinogenicity in humans.
Group 4: The agent (mixture, exposure circumstance) is probably not carcinogenic to humans.
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Last updated: 22 July 2004